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The Immune System Could Help Save Lives from Bowel Cancer
Leading this research is Immunologist Dr Kevin Fenix from the Basil Hetzel Institute for Translational Health Research who is investigating a group of immune cells that could be a key target to predict whether a patient’s bowel cancer is likely to spread.
“When bowel cancer is diagnosed early, patients have a 90 per cent cure rate with the treatments currently available to them,” Dr Fenix said.
“It’s when the cancer reaches stage two and three that it becomes a problem. While the surgeon can remove the cancer, there is a 50 per cent chance of it returning and spreading to other areas of the body, most commonly the liver. It’s at this stage where people sadly succumb to the disease.”
Dr Fenix’s discovery could see clinicians be able to predict when a patient’s cancer is more likely to spread or return, meaning they can be more closely monitored.
“We are very lucky to have access to a bank that stores the tissue samples of patients who have had their cancer tumour removed through surgery. With these samples spanning a 20 year period, we’ve been able to track these patients over time and discovered those whose cancer sadly did end up returning had high levels of this immune cell.
“Now we are trying to understand these cells more, how they interact and what role they place in helping cancer to spread through a person’s body.”
While in the early stages, Dr Fenix is hopeful his research could lead to a new way of detecting and treating bowel cancer.
“After the patient has their surgery, we hope the clinicians will be able to test their tissue for these immune cells to determine how likely it is for their cancer to return and spread. Once we understand the cells more we’ll know if there is potential for a new treatment based on this finding.”
Whilst in its early stages, this research could save the lives of so many diagnosed with bowel cancer in the future. Sign up to host a Longest Table and let’s beat bowel cancer together.